The calcium dynamics of human dental pulp stem cells stimulated with tricalcium silicate-based cements determine their differentiation and mineralization outcome

Abstract Calcium (Ca2+) signalling plays an indispensable role in dental pulp and dentin regeneration, but the Ca2+ responses of human dental pulp stem cells (hDPSCs) stimulated with tricalcium silicate-based (TCS-based) dental biomaterials remains largely unexplored. The objective of the present st...

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Bibliographic Details
Main Authors: Elanagai Rathinam, Srinath Govindarajan, Sivaprakash Rajasekharan, Heidi Declercq, Dirk Elewaut, Peter De Coster, Luc Martens, Luc Leybaert
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80096-5