Dual Anta-Inhibitors Targeting Protein Kinase CK1δ and A<sub>2A</sub> Adenosine Receptor Useful in Neurodegenerative Disorders

Dual Anta-Inhibitors Targeting Protein Kinase CK1δ and A<sub>2A</sub> Adenosine Receptor Useful in Neurodegenerative Disorders

Currently, the number of patients with neurodegenerative pathologies is estimated at over one million, with consequences also on the economic level. Several factors contribute to their development, including overexpression of A<sub>2A</sub> adenosine receptors (A<sub>2A</sub>...

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Bibliographic Details
Main Authors: Beatrice Francucci, Simone Angeloni, Diego Dal Ben, Catia Lambertucci, Massimo Ricciutelli, Andrea Spinaci, Aleksei Smirnov, Rosaria Volpini, Michela Buccioni, Gabriella Marucci
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
A<sub>2A</sub>AR antagonists
CK1δ inhibitors
A<sub>2A</sub>/CK1δ dual inhibitors
neuroinflammation
cytokine
neuroprotection
Online Access:https://www.mdpi.com/1420-3049/28/12/4762

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https://www.mdpi.com/1420-3049/28/12/4762

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