Light microscopy based approach for mapping connectivity with molecular specificity
Mapping neuroanatomy is a foundational goal of connectomics, and the gold standard method is electron microscopy as light microscopy lacks nanoscale resolution. Here the authors develop a strategy using multicolor genetic labeling (Brainbow) and expansion microscopy to map putative synaptic connecti...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-09-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-18422-8 |