Sonodynamic effect based on vancomycin-loaded microbubbles or meropenem-loaded microbubbles enhances elimination of different biofilms and bactericidal efficacy

Sonodynamic effect based on vancomycin-loaded microbubbles or meropenem-loaded microbubbles enhances elimination of different biofilms and bactericidal efficacy

Aims: This study investigated vancomycin-microbubbles (Vm-MBs) and meropenem (Mp)-MBs with ultrasound-targeted microbubble destruction (UTMD) to disrupt biofilms and improve bactericidal efficiency, providing a new and promising strategy for the treatment of device-related infections (DRIs). Method...

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Bibliographic Details
Main Authors: Liqin Yao, Chenghan Chu, Yicheng Li, Li Cao, Jianhua Yang, Wenbo Mu
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2024-09-01
Series:Bone & Joint Research
Subjects:
methicillin-resistant staphylococcus aureus
escherichia coli
biofilm
vancomycin
meropenem
ultrasound-targeted microbubble destruction technology
biofilms
antibiotics
methicillin-resistant staphylococcus aureus (mrsa)
infections
staining
scanning electron microscopy
bacteria
t-test
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.139.BJR-2023-0319.R3

Internet

https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.139.BJR-2023-0319.R3

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