The Pharmacological Effect and Mechanism of Lanthanum Hydroxide on Vascular Calcification Caused by Chronic Renal Failure Hyperphosphatemia

The Pharmacological Effect and Mechanism of Lanthanum Hydroxide on Vascular Calcification Caused by Chronic Renal Failure Hyperphosphatemia

ObjectiveThe present work aimed to explore the efficacy of lanthanum hydroxide in managing the vascular calcification induced by hyperphosphate in chronic renal failure (CRF) as well as the underlying mechanism.MethodsRats were randomly allocated to five groups: normal diet control, CKD hyperphospha...

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Bibliographic Details
Main Authors: Lulu Zhao, Shengnan Wang, Hong Liu, Xiaoli Du, Ren Bu, Bing Li, Ruilan Han, Jie Gao, Yang Liu, Jian Hao, Jianrong Zhao, Yan Meng, Gang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
lanthanum hydroxide
vascular calcification
chronic renal failure
hyperphosphatemia
pharmacological effect
mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.639127/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.639127/full

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