The mycosis fungoides cutaneous microenvironment shapes dysfunctional cell trafficking, antitumor immunity, matrix interactions, and angiogenesis

Malignant T lymphocyte proliferation in mycosis fungoides (MF) is largely restricted to the skin, implying that malignant cells are dependent on their specific cutaneous tumor microenvironment (TME), including interactions with non-malignant immune and stromal cells, cytokines, and other immunomodul...

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Bibliographic Details
Main Authors: Alyxzandria M. Gaydosik, Connor J. Stonesifer, Tracy Tabib, Robert Lafyatis, Larisa J. Geskin, Patrizia Fuschiotti
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-10-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.170015