G-Protein α-Subunit Gsα Is Required for Craniofacial Morphogenesis.

The heterotrimeric G protein subunit Gsα couples receptors to activate adenylyl cyclase and is required for the intracellular cAMP response and protein kinase A (PKA) activation. Gsα is ubiquitously expressed in many cell types; however, the role of Gsα in neural crest cells (NCCs) remains unclear....

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Bibliographic Details
Main Authors: Run Lei, Ke Zhang, Yanxia Wei, Min Chen, Lee S Weinstein, Yang Hong, Minyan Zhu, Hongchang Li, Huashun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4747491?pdf=render