The MRGPRX2-substance P pathway regulates mast cell migration

Summary: Mast cells (MCs) are tissue-resident immune cells known to degranulate in response to FcεRI crosslinking or MRGPRX2 engagement. MCs are found close to nerves, but the mechanisms that regulate this privileged localization remain unclear. Here, we investigated MRGPRX2 expression patterns and...

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Bibliografische gegevens
Hoofdauteurs: Peter W. West, Jérémy Chéret, Rajia Bahri, Orsolya Kiss, Zining Wu, Colin H. Macphee, Silvia Bulfone-Paus
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2024-10-01
Reeks:iScience
Onderwerpen:
Online toegang:http://www.sciencedirect.com/science/article/pii/S2589004224022090