Tandem Mass Spectrometry as Strategy for the Selective Identification and Quantification of the Amyloid Precursor Protein Tyr682 Residue Phosphorylation Status in Human Blood Mononuclear Cells

Tandem Mass Spectrometry as Strategy for the Selective Identification and Quantification of the Amyloid Precursor Protein Tyr682 Residue Phosphorylation Status in Human Blood Mononuclear Cells

<b>Background:</b> Alzheimer’s disease (AD) is a devastating neurodegenerative disease without guidelines for early diagnosis or personalized treatment. Previous studies have highlighted a crucial role of increasing phosphorylation levels of the amyloid precursor protein (APP) Tyr682 res...

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Bibliografiske detaljer
Main Authors: Pierluigi Reveglia, Rosarita Nasso, Antonella Angiolillo, Lucia Lecce, Carmela Paolillo, Samantha De Tullio, Monica Gelzo, Alfonso Di Costanzo, Carmela Matrone, Gaetano Corso
Format: Article
Sprog:English
Udgivet: MDPI AG 2021-08-01
Serier:Biomolecules
Fag:
Alzheimer’s disease
APP Tyr682 phosphorylation
targeted peptide analysis
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https://www.mdpi.com/2218-273X/11/9/1297

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