Sialoadhesin expressed on IFN-induced monocytes binds HIV-1 and enhances infectivity.
HIV-1 infection dysregulates the immune system and alters gene expression in circulating monocytes. Differential gene expression analysis of CD14(+) monocytes from subjects infected with HIV-1 revealed increased expression of sialoadhesin (Sn, CD169, Siglec 1), a cell adhesion molecule first describ...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-04-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2288672?pdf=render |