Sialoadhesin expressed on IFN-induced monocytes binds HIV-1 and enhances infectivity.

Sialoadhesin expressed on IFN-induced monocytes binds HIV-1 and enhances infectivity.

HIV-1 infection dysregulates the immune system and alters gene expression in circulating monocytes. Differential gene expression analysis of CD14(+) monocytes from subjects infected with HIV-1 revealed increased expression of sialoadhesin (Sn, CD169, Siglec 1), a cell adhesion molecule first describ...

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Bibliographic Details
Main Authors: Hans Rempel, Cyrus Calosing, Bing Sun, Lynn Pulliam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2288672?pdf=render

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