Oxidized low-density lipoprotein causes ribosome reduction and inhibition of protein synthesis in retinal pigment epithelial cells

Oxidized low-density lipoprotein causes ribosome reduction and inhibition of protein synthesis in retinal pigment epithelial cells

Retinal pigment epithelium (RPE) are specialized multifunctional cells indispensable for maintenance of vision. Dysfunction and death of the RPE cells is implicated in the genesis and progression of age-related macular degeneration (AMD). Oxidative stress and resulting cellular damage plays a critic...

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Bibliographic Details
Main Authors: Francesco Giorgianni, Sarka Beranova-Giorgianni
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Retinal pigment epithelium
Oxidized LDL
Drusen
Proteome
Oxidative stress
Proteostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822001455

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http://www.sciencedirect.com/science/article/pii/S2405580822001455

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