Accumulation of LDL/ox-LDL in the necrotic region participates in osteonecrosis of the femoral head: a pathological and in vitro study

Accumulation of LDL/ox-LDL in the necrotic region participates in osteonecrosis of the femoral head: a pathological and in vitro study

Abstract Background Osteonecrosis of the femoral head (ONFH) is a common but intractable disease that appears to involve lipid metabolic disorders. Although numerous studies have demonstrated that high blood levels of low-density lipoprotein (LDL) are closely associated with ONFH, there is limited e...

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Bibliographic Details
Main Authors: Xin-Yuan Wang, Tian-Le Ma, Kang-Ning Chen, Zhi-Ying Pang, Hao Wang, Jun-Ming Huang, Guo-Bin Qi, Chen-Zhong Wang, Zeng-Xin Jiang, Lin-Jing Gong, Zhe Wang, Chang Jiang, Zuo-Qin Yan
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Lipids in Health and Disease
Subjects:
Osteonecrosis of the femoral head
Low-density lipoprotein
Oxidized low-density lipoprotein
Osteocyte
Hypoxia
Online Access:https://doi.org/10.1186/s12944-021-01601-x

Internet

https://doi.org/10.1186/s12944-021-01601-x

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