Influence of Potassium Ions on Act of Amphotericin B to the DPPC/Chol Mixed Monolayer at Different Surface Pressures

Amphotericin B (AmB) is an antifungal drug that rarely develops resistance. It has an affinity with the cholesterol on mammalian cell membranes, disrupting the structure and function of the membranes, which are also affected by potassium ions. However, the mechanism is unclear. In this paper, the La...

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Bibliographic Details
Main Author: Juan Wang
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/12/1/84