Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression

Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression

Neurogenesis decline in hippocampal dentate gyrus (DG) participates in stress-induced depressive-like behaviors, but the underlying mechanism remains poorly understood. Here, we observed low-expression of NOD-like receptor family pyrin domain containing 6 (NLRP6) in hippocampus of stress-stimulated...

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Bibliographic Details
Main Authors: Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li, Lingdong Kong
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Acta Pharmaceutica Sinica B
Subjects:
NLRP6
Neural stem cells
Stress resilience
Depressive-like behaviors
ECRG4
Mitochondrial function
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523000990

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http://www.sciencedirect.com/science/article/pii/S2211383523000990

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