Full-length RNA-Seq of the RHOH gene in human B cells reveals new exons and splicing patterns

Full-length RNA-Seq of the RHOH gene in human B cells reveals new exons and splicing patterns

Abstract The RhoH protein is a member of the Ras superfamily of guanosine triphosphate-binding proteins. RhoH is an atypical Rho family member that is always GTP-bound and thus always activated. It is restrictively expressed in normal hematopoietic cells, where it is a negative regulator of cell gro...

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Bibliographic Details
Main Authors: Frédéric Leprêtre, Jean-Pascal Meneboo, Céline Villenet, Laure Delestré, Bruno Quesnel, Carl Simon Shelley, Martin Figeac, Sylvie Galiègue-Zouitina
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
RHOH gene
Full-length targeted mRNA-Seq
Oxford Nanopore Technologies
New exons
New transcripts
Gene fusion
Online Access:https://doi.org/10.1038/s41598-024-79307-0

Internet

https://doi.org/10.1038/s41598-024-79307-0

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