miR-15a-5p regulates myocardial fibrosis in atrial fibrillation by targeting Smad7

Background At present, there is no effective treatment for myocardial fibrosis in atrial fibrillation (AF). It is reported that miR-15a-5p is abnormally expressed in AF patients but its specific role remains unclear. This study aims to investigate the effect of miR-15a-5p in myocardial fibrosis. Met...

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Bibliographic Details
Main Authors: Dan He, Zhong-bao Ruan, Gui-xian Song, Ge-cai Chen, Fei Wang, Mei-xiang Wang, Mao-kun Yuan, Li Zhu
Format: Article
Language:English
Published: PeerJ Inc. 2021-12-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/12686.pdf