Sex Dimorphism of Allergen-Induced Secreted Proteins in Murine and Human Lungs

Biological sex influences disease severity, prevalence and response to therapy in allergic asthma. However, allergen-mediated sex-specific changes in lung protein biomarkers remain undefined. Here, we report sex-related differences in specific proteins secreted in the lungs of both mice and humans,...

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Bibliographic Details
Main Authors: Mahadevappa Hemshekhar, Dina H. D. Mostafa, Victor Spicer, Hadeesha Piyadasa, Danay Maestre-Batlle, Anette K. Bolling, Andrew J. Halayko, Christopher Carlsten, Neeloffer Mookherjee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.923986/full