Human Umbilical Cord Blood Serum–derived α-Secretase

Alzheimer’s disease (AD) is an age-related disorder that affects cognition. Our previous studies showed that the neuroprotective fragment of amyloid procurer protein (APP) metabolite, soluble APPα (sAPPα), interferes with β-site APP-cleaving enzyme 1 (BACE1, β-secretase) cleavage and reduces amyloid...

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Bibliographic Details
Main Authors: Ahsan Habib, Huayan Hou, Takashi Mori, Jun Tian, Jin Zeng, Shengnuo Fan, Brian Giunta, Paul R. Sanberg, Darrell Sawmiller, Jun Tan
Format: Article
Language:English
Published: SAGE Publishing 2018-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/0963689718759473