Increased Circulating Soluble Junctional Adhesion Molecules in Systemic Sclerosis: Association with Peripheral Microvascular Impairment

Increased Circulating Soluble Junctional Adhesion Molecules in Systemic Sclerosis: Association with Peripheral Microvascular Impairment

Systemic sclerosis (SSc, scleroderma) is a severe disease characterized by peripheral microcirculation abnormalities manifesting with Raynaud’s phenomenon, nailfold videocapillaroscopic (NVC) changes, and even ischemic digital ulcers (DUs) that are often refractory to treatments. In the wake of prev...

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Bibliographic Details
Main Authors: Eloisa Romano, Irene Rosa, Bianca Saveria Fioretto, Marco Matucci-Cerinic, Mirko Manetti
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Life
Subjects:
systemic sclerosis
scleroderma
junctional adhesion molecules
sJAM-A
sJAM-C
peripheral microvascular damage
Online Access:https://www.mdpi.com/2075-1729/12/11/1790

Internet

https://www.mdpi.com/2075-1729/12/11/1790

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