Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors

Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors

In order to achieve selective targeting of affinity–ligand coated nanoparticles to the target tissue, it is essential to understand the key mechanisms that govern their capture by the target cell. Next-generation pharmacokinetic (PK) models that systematically account for proteomic and mechanical fa...

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Podrobná bibliografie
Hlavní autoři: N. Ramakrishnan, Richard W. Tourdot, David M. Eckmann, Portonovo S. Ayyaswamy, Vladimir R. Muzykantov, Ravi Radhakrishnan
Médium: Článek
Jazyk:English
Vydáno: The Royal Society 2016-01-01
Edice:Royal Society Open Science
Témata:
functionalized nanocarrier
membrane biophysics
excess area
On-line přístup:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.160260

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.160260

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