Reduced Interaction of Aggregated α-Synuclein and VAMP2 by Environmental Enrichment Alleviates Hyperactivity and Anxiety in a Model of Parkinson’s Disease

Parkinson’s disease (PD) is a prevalent motor disease caused by the accumulation of mutated α-synuclein (α-Syn); however, its early stages are also characterized by non-motor symptoms, such as olfactory loss, cognitive decline, depression, and anxiety. The therapeutic effects of environmental enrich...

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Bibliographic Details
Main Authors: Kyungri Kim, Soohyun Wi, Jung Hwa Seo, Soonil Pyo, Sung-Rae Cho
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/3/392