High-throughput immune repertoire analysis with IGoR
B and T cell receptor diversity can be studied by high-throughput immune receptor sequencing. Here, the authors develop a software tool, IGoR, that calculates the likelihoods of potential V(D)J recombination and somatic hypermutation scenarios from raw immune sequence reads.
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-02832-w |