High-throughput immune repertoire analysis with IGoR

B and T cell receptor diversity can be studied by high-throughput immune receptor sequencing. Here, the authors develop a software tool, IGoR, that calculates the likelihoods of potential V(D)J recombination and somatic hypermutation scenarios from raw immune sequence reads.

Bibliographic Details
Main Authors: Quentin Marcou, Thierry Mora, Aleksandra M. Walczak
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-02832-w