Neuroprotection by Nrf2 via modulating microglial phenotype and phagocytosis after intracerebral hemorrhage

Neuroprotection by Nrf2 via modulating microglial phenotype and phagocytosis after intracerebral hemorrhage

Activated microglia are divided into pro-inflammatory and anti-inflammatory functional states. In anti-inflammatory state, activated microglia contribute to phagocytosis, neural repair and anti-inflammation. Nrf2 as a major endogenous regulator in hematoma clearance after intracerebral hemorrhage (I...

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Bibliographic Details
Main Authors: Chuntian Liang, Lirong Liu, Shuangjin Bao, Zhenjia Yao, Qinqin Bai, Pengcheng Fu, Xiangyu Liu, John H. Zhang, Gaiqing Wang
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Heliyon
Subjects:
Microglial phenotype
Phagocytosis
Nrf2
Hematoma clearance
Intracerebral hemorrhage
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023009842

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http://www.sciencedirect.com/science/article/pii/S2405844023009842

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