Methionine oxidation selectively enhances T cell reactivity against a melanoma antigen

Methionine oxidation selectively enhances T cell reactivity against a melanoma antigen

Summary: The impact of the peptide amino acids side-chain modifications on the immunological recognition has been scarcely explored. We investigate here the effect of methionine oxidation on the antigenicity of the melanoma immunodominant peptide 369-YMDGTMSQV-377 (YMD). Using CD8+ T cell activation...

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Bibliographic Details
Main Authors: Gabriela N. Chiriţoiu, Cristian V.A. Munteanu, Teodor A. Şulea, Laurenţiu Spiridon, Andrei-Jose Petrescu, Camilla Jandus, Pedro Romero, Ştefana M. Petrescu
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Immunology
Biochemistry
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012828

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223012828

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