Key roles of autophagosome/endosome maturation mediated by Syntaxin17 in methamphetamine-induced neuronal damage in mice

Key roles of autophagosome/endosome maturation mediated by Syntaxin17 in methamphetamine-induced neuronal damage in mice

Abstract Background Autophagic defects are involved in Methamphetamine (Meth)-induced neurotoxicity. Syntaxin 17 (Stx17), a member of the SNARE protein family, participating in several stages of autophagy, including autophagosome-late endosome/lysosome fusion. However, the role of Stx17 and potentia...

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Hlavní autoři: Xi Wang, Miaoyang Hu, Jingrong Chen, Xinyu Lou, Hongchao Zhang, Muhan Li, Jie Cheng, Tengfei Ma, Jianping Xiong, Rong Gao, Xufeng Chen, Jun Wang
Médium: Článek
Jazyk:English
Vydáno: BMC 2024-01-01
Edice:Molecular Medicine
Témata:
Methamphetamine
Syntaxin 17
Autophagy
Autophagosome
Endosome
On-line přístup:https://doi.org/10.1186/s10020-023-00765-9

Internet

https://doi.org/10.1186/s10020-023-00765-9

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