Indomethacin can downregulate the levels of inflammatory mediators in the hippocampus of rats submitted to pilocarpine-induced status epilepticus

OBJECTIVE: Refractory status epilepticus is one of the most life-threatening neurological emergencies and is characterized by high morbidity and mortality. Additionally, the use of anti-inflammatory drugs during this period is very controversial. Thus, this study has been designed to analyze the eff...

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Bibliographic Details
Main Authors: Michele Juliane Vieira, Sandra Regina Perosa, Gustavo Adolfo Argaãaraz, José Antônio Silva Jr, Esper Abrão Cavalheiro, Maria da Graça Naffah-Mazzacoratti
Format: Article
Language:English
Published: Elsevier España 2014-09-01
Series:Clinics
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322014000900621&lng=en&tlng=en