Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions

Renal interstitial fibroblasts coproduce erythropoietin and renin under anaemic conditions

Background: Erythrocyte mass contributes to maintaining systemic oxygen delivery and blood viscosity, with the latter being one of the determinants of blood pressure. However, the physiological response to blood pressure changes under anaemic conditions remain unknown. Methods and Findings: We show...

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Bibliographic Details
Main Authors: Kenichiro Miyauchi, Taku Nakai, Sakae Saito, Tae Yamamoto, Koji Sato, Koichiro Kato, Masahiro Nezu, Mariko Miyazaki, Sadayoshi Ito, Masayuki Yamamoto, Norio Suzuki
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:EBioMedicine
Subjects:
Erythropoiesis
Hypoxia
Renal anaemia
Renin-angiotensin system
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421000025

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http://www.sciencedirect.com/science/article/pii/S2352396421000025

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