JTE-013 Alleviates Pulmonary Fibrosis by Affecting the RhoA/YAP Pathway and Mitochondrial Fusion/Fission

JTE-013 Alleviates Pulmonary Fibrosis by Affecting the RhoA/YAP Pathway and Mitochondrial Fusion/Fission

Pulmonary fibrosis may be due to the proliferation of fibroblasts and the aggregation of extracellular matrix, resulting in the stimulation of inflammation damage, destroying lung tissue structure, seriously affecting the patient’s respiratory function, and even leading to death. We investigated the...

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Bibliographic Details
Main Authors: Jiaxu Zhou, Yilan Song, Xingmei Wang, Xinrui Li, Chang Liu, Chenchen Tian, Chongyang Wang, Liangchang Li, Guanghai Yan, Hong Cui
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceuticals
Subjects:
JTE-013
S1PR2
lung epithelial cells
RHOA/YAP
mitochondrial fusion/fission
pulmonary fibrosis
Online Access:https://www.mdpi.com/1424-8247/16/10/1444

Internet

https://www.mdpi.com/1424-8247/16/10/1444

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