IgG subclass and Fc glycosylation shifts are linked to the transition from pre- to inflammatory autoimmune conditions

A crucial factor for the development of inflammatory autoimmune diseases is the occurrence of antibodies directed against self-tissues and structures, which leads to damage and inflammation. While little is known about the cause of the development of mis-directed, disease-specific T and B cells and...

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Bibliographic Details
Main Authors: Jana Sophia Buhre, Mareike Becker, Marc Ehlers
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1006939/full