Psoralea corylifolia extract induces vasodilation in rat arteries through both endothelium-dependent and -independent mechanisms involving inhibition of TRPC3 channel activity and elaboration of prostaglandin

Psoralea corylifolia extract induces vasodilation in rat arteries through both endothelium-dependent and -independent mechanisms involving inhibition of TRPC3 channel activity and elaboration of prostaglandin

Context: Fructus Psoralea, Psoralea corylifolia L. (Leguminosae), has been widely used in traditional medicines for the treatment of dermatitis, leukoderma, asthma and osteoporosis. Objectives: In this study, we sought to study mechanisms underlying the vasoactive properties of Psoralea corylifolia...

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Bibliographic Details
Main Authors: Addis Kassahun Gebremeskel, Tharaka Darshana Wijerathne, Ji Hyun Kim, Min Ji Kim, Chang-Seob Seo, Hyeun-Kyoo Shin, Kyu Pil Lee
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Pharmaceutical Biology
Subjects:
ethanol extract
hypotensive
nitric oxide
cox
non-selective cation channel
Online Access:http://dx.doi.org/10.1080/13880209.2017.1383484

Internet

http://dx.doi.org/10.1080/13880209.2017.1383484

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