The HIF-1α and mTOR Pathways Amplify Heterotopic Ossification
Fibrodysplasia ossificans progressiva (FOP; MIM# 135100) is an ultra-rare congenital disorder caused by gain-of-function point mutations in the Activin receptor A type I (<i>ACVR1</i>, also known as <i>ALK2</i>) gene. FOP is characterized by episodic heterotopic ossification...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-01-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/14/2/147 |