VprBP/DCAF1 Triggers Melanomagenic Gene Silencing through Histone H2A Phosphorylation

Vpr binding protein (VprBP), also known as DDB1- and CUL4-associated factor1 (DCAF1), is a recently identified atypical kinase and plays an important role in downregulating the transcription of tumor suppressor genes as well as increasing the risk for colon and prostate cancers. Melanoma is the most...

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Bibliographic Details
Main Authors: Yonghwan Shin, Sungmin Kim, Gangning Liang, Tobias S. Ulmer, Woojin An
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/9/2552