A Novel Druggable Dual-Specificity tYrosine-Regulated Kinase3/Calmodulin Kinase-like Vesicle-Associated Signaling Module with Therapeutic Implications in Neuroblastoma

A Novel Druggable Dual-Specificity tYrosine-Regulated Kinase3/Calmodulin Kinase-like Vesicle-Associated Signaling Module with Therapeutic Implications in Neuroblastoma

High-risk neuroblastoma is a very aggressive pediatric cancer, accounting for ~15% of childhood cancer mortality. Therefore, novel therapeutic strategies for the treatment of neuroblastoma are urgently sought. Here, we focused on the potential implications of the Dual-specificity tYrosine-Regulated...

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Bibliographic Details
Main Authors: Esteban J. Rozen, Kim Wigglesworth, Jason M. Shohet
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
DYRK3
CAMKV
neuroblastoma
cell proliferation
mitotic spindle
biomolecular condensates
Online Access:https://www.mdpi.com/2227-9059/12/1/197

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https://www.mdpi.com/2227-9059/12/1/197

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