Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming.

Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming.

<h4>Aims/hypothesis</h4>Duct cells isolated from adult human pancreas can be reprogrammed to express islet beta cell genes by adenoviral transduction of the developmental transcription factor neurogenin3 (Ngn3). In this study we aimed to fully characterize the extent of this reprogrammin...

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Main Authors: Nathalie Swales, Geert A Martens, Stefan Bonné, Yves Heremans, Rehannah Borup, Mark Van de Casteele, Zhidong Ling, Daniel Pipeleers, Philippe Ravassard, Finn Nielsen, Jorge Ferrer, Harry Heimberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22606327/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22606327/?tool=EBI

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