Unprecedented synthesis of a 14-membered hexaazamacrocycle

The transformation of 3-[(ethoxymethylene)amino]-1-methyl-1H-pyrazole-4-carbonitrile into the 14-membered macrocycle, 2,10-dimethyl-2,8,10,16-tetrahydrodipyrazolo[3,4-e:3',4'-l][1,2,4,8,9,11]hexaazacyclotetradecine-4,12-diamine, by the reaction with excess hydrazine under various condition...

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Bibliographic Details
Main Authors: Anastasia A. Fesenko, Anatoly D. Shutalev
Format: Article
Language:English
Published: Beilstein-Institut 2023-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.19.126