Efferocyte‐Derived MCTRs Metabolically Prime Macrophages for Continual Efferocytosis via Rac1‐Mediated Activation of Glycolysis

Abstract Clearance of multiple rounds of apoptotic cells (ACs) through continual efferocytosis is critical in the maintenance of organ function, the resolution of acute inflammation, and tissue repair. To date, little is known about the nature of mechanisms and factors that govern this fundamental p...

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Bibliographic Details
Main Authors: Duco Steven Koenis, Roberta de Matteis, Vinothini Rajeeve, Pedro Cutillas, Jesmond Dalli
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202304690