Alleviating psoriatic skin inflammation through augmentation of Treg cells via CTLA-4 signaling peptide

Psoriasis is a chronic inflammatory skin disease characterized by hyperplasia of keratinocytes and immune cell infiltration. The IL-17-producing T cells play a key role in psoriasis pathogenesis, while regulatory T (Treg) cells are diminished during psoriatic inflammation. Current psoriasis treatmen...

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Bibliographic Details
Main Authors: Woo-Sung Lee, Kyung-Ho Nam, Jong Hoon Kim, Won-Ju Kim, Jeong Eun Kim, Eui-Cheol Shin, Gil-Ran Kim, Je-Min Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1233514/full