Identifying the critical state of cancers by single-sample Markov flow entropy

Background The progression of complex diseases sometimes undergoes a drastic critical transition, at which the biological system abruptly shifts from a relatively healthy state (before-transition stage) to a disease state (after-transition stage). Searching for such a critical transition or critical...

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Bibliographic Details
Main Authors: Juntan Liu, Yuan Tao, Ruoqi Lan, Jiayuan Zhong, Rui Liu, Pei Chen
Format: Article
Language:English
Published: PeerJ Inc. 2023-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/15695.pdf