Retinoic acid signalling in fibro/adipogenic progenitors robustly enhances muscle regeneration

Retinoic acid signalling in fibro/adipogenic progenitors robustly enhances muscle regeneration

Background: During muscle regeneration, excessive formation of adipogenic and fibrogenic tissues, from their respective fibro/adipogenic progenitors (FAPs), impairs functional recovery. Intrinsic mechanisms controlling the proliferation and differentiation of FAPs remain largely unexplored. Methods:...

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Bibliographic Details
Main Authors: Liang Zhao, Jun Seok Son, Bo Wang, Qiyu Tian, Yanting Chen, Xiangdong Liu, Jeanene M. de Avila, Mei-Jun Zhu, Min Du
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:EBioMedicine
Subjects:
Fibro/adipogenic progenitors
Retinoic acid signalling
Muscle regeneration
Fibrosis
Adipogenesis
Obesity
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420303960

Internet

http://www.sciencedirect.com/science/article/pii/S2352396420303960

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