Receptor–Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment

Receptor–Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment

Due to the binding to a number of proteins to the receptor protomers in receptor heteromers in the brain, the term “heteroreceptor complexes” was introduced. A number of serotonin 5-HT1A heteroreceptor complexes were recently found to be linked to the ascending 5-HT pathways know...

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Bibliographic Details
Main Authors: Dasiel O. Borroto-Escuela, Manuel Narváez, Patrizia Ambrogini, Luca Ferraro, Ismel Brito, Wilber Romero-Fernandez, Yuniesky Andrade-Talavera, Antonio Flores-Burgess, Carmelo Millon, Belen Gago, Jose Angel Narvaez, Yuji Odagaki, Miklos Palkovits, Zaida Diaz-Cabiale, Kjell Fuxe
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
heteroreceptor complexes
G protein-coupled receptors
oligomerization
receptor-receptor interactions
serotonin 5-HT1A receptor
depression
galanin
receptor tyrosine kinase
fibroblast growth factor receptor
Online Access:http://www.mdpi.com/1420-3049/23/6/1341

Internet

http://www.mdpi.com/1420-3049/23/6/1341

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