Radiotherapy Scheme Effect on PD-L1 Expression for Locally Advanced Rectal Cancer

Radiotherapy Scheme Effect on PD-L1 Expression for Locally Advanced Rectal Cancer

In locally advanced rectal cancer, radiotherapy (RT) followed by surgery have improved locoregional control, but distant recurrences remain frequent. Although checkpoint inhibitors have demonstrated objective response in several cancers, the clinical benefit of PD-1/PD-L1 blockade remains uncertain...

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Bibliographic Details
Main Authors: Jihane Boustani, Valentin Derangère, Aurélie Bertaut, Olivier Adotevi, Véronique Morgand, Céline Charon-Barra, François Ghiringhelli, Céline Mirjolet
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
rectal cancer
neoadjuvant radiotherapy
fractionation
PD-L1 expression
Online Access:https://www.mdpi.com/2073-4409/9/9/2071

Internet

https://www.mdpi.com/2073-4409/9/9/2071

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