Autologous bone marrow-derived mononuclear cells transplantation in type 2 diabetes mellitus: effect on β-cell function and insulin sensitivity

Autologous bone marrow-derived mononuclear cells transplantation in type 2 diabetes mellitus: effect on β-cell function and insulin sensitivity

Abstract Background Insulin resistance and insulin deficiency are the cardinal defects in the pathogenesis of type 2 diabetes mellitus (T2DM). Despite the plethora of anti-diabetic medications, drugs specifically targeting the β-cells are still desired. Stem cell therapy has emerged as a novel thera...

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Bibliographic Details
Main Authors: Shobhit Bhansali, Pinaki Dutta, Mukesh Kumar Yadav, Ashish Jain, Sunder Mudaliar, Meredith Hawkins, Anura V. Kurpad, Deepak Pahwa, Ashok Kumar Yadav, Ratti Ram Sharma, Vivekanand Jha, Neelam Marwaha, Shipra Bhansali, Anil Bhansali
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Diabetology & Metabolic Syndrome
Subjects:
T2DM
Stem cells
Autologous bone marrow-derived mononuclear cells
Online Access:http://link.springer.com/article/10.1186/s13098-017-0248-7

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http://link.springer.com/article/10.1186/s13098-017-0248-7

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