Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke

Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke

Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to remyelination. Failure of remyelination due to oligodendrocyte progenitor cell death can result in severe nerve damage. Ferroptosis is an iron-dependent form of regulated cell death caused...

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Bibliographic Details
Main Authors: Jian Yang, Jiang Wu, Xueshun Xie, Pengfei Xia, Jinxin Lu, Jiale Liu, Lei Bai, Xiang Li, Zhengquan Yu, Haiying Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-07-01
Series:Neural Regeneration Research
Subjects:
bioinformatics
bulk rna sequencing
ferroptosis
ischemic stroke
myelin injury
oligodendrocyte progenitor cell
perilipin-2
single-cell rna sequencing
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-23-01540

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https://journals.lww.com/10.4103/NRR.NRR-D-23-01540

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