Complete Reversible Refolding of a G-Protein Coupled Receptor on a Solid Support.

The factors defining the correct folding and stability of integral membrane proteins are poorly understood. Folding of only a few select membrane proteins has been scrutinised, leaving considerable deficiencies in knowledge for large protein families, such as G protein coupled receptors (GPCRs). Com...

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Bibliographic Details
Main Authors: Natalie Di Bartolo, Emma L R Compton, Tony Warne, Patricia C Edwards, Christopher G Tate, Gebhard F X Schertler, Paula J Booth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4794186?pdf=render