Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.

Cellular restriction factors help to defend humans against human immunodeficiency virus (HIV). HIV accessory proteins hijack at least three different Cullin-RING ubiquitin ligases, which must be activated by the small ubiquitin-like protein NEDD8, in order to counteract host cellular restriction fac...

Full description

Bibliographic Details
Main Authors: David J Stanley, Koen Bartholomeeusen, David C Crosby, Dong Young Kim, Eunju Kwon, Linda Yen, Nathalie Caretta Cartozo, Ming Li, Stefanie Jäger, Jeremy Mason-Herr, Fumiaki Hayashi, Shigeyuki Yokoyama, Nevan J Krogan, Reuben S Harris, Boris Matija Peterlin, John D Gross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-12-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003085&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003085&type=printable

Similar Items