In silico analysis of the HSP90 chaperone system from the African trypanosome, Trypanosoma brucei

In silico analysis of the HSP90 chaperone system from the African trypanosome, Trypanosoma brucei

African trypanosomiasis is a neglected tropical disease caused by Trypanosoma brucei (T. brucei) and spread by the tsetse fly in sub-Saharan Africa. The trypanosome relies on heat shock proteins for survival in the insect vector and mammalian host. Heat shock protein 90 (HSP90) plays a crucial role...

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Bibliographic Details
Main Authors: Miebaka Jamabo, Stephen John Bentley, Paula Macucule-Tinga, Praise Tembo, Adrienne Lesley Edkins, Aileen Boshoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
African trypanosomiasis
Trypanosoma brucei
HSP90
molecular chaperones
co-chaperone
heat shock proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.947078/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.947078/full

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