EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance

EpCAM-dependent extracellular vesicles from intestinal epithelial cells maintain intestinal tract immune balance

The intestinal tract is continually exposed to foreign material and gut homeostasis is dependent on tolerance. Here, the authors show that extracellular vesicles released from intestinal epithelial cells stimulate T regulatory cells and immunosuppressive dendritic cells.

Bibliographic Details
Main Authors: Lingling Jiang, Yingying Shen, Danfeng Guo, Diya Yang, Jiajun Liu, Xuefeng Fei, Yunshan Yang, Buyi Zhang, Zhendong Lin, Fei Yang, Xiaojian Wang, Keyi Wang, Jianli Wang, Zhijian Cai
Format: Article
Language:English
Published: Nature Portfolio 2016-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13045

Internet

https://doi.org/10.1038/ncomms13045

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