Elevated von Willebrand factor levels during heavy menstrual bleeding episodes limit the diagnostic utility for von Willebrand disease

Abstract Background Heavy menstrual bleeding (HMB) is often the first bleeding symptom for female individuals with inherited bleeding disorders. Guidelines recommend performing the hemostatic evaluation at HMB presentation. Von Willebrand factor (VWF) levels increase with stress, making it unclear i...

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Bibliographic Details
Main Authors: Megan C. Brown, Michael H. White, Rachel Friedberg, Kalinda Woods, Krista Childress, Mona Kulkarni, Robert F. Sidonio Jr
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12513