A New Phenotype in Candida-Epithelial Cell Interaction Distinguishes Colonization- versus Vulvovaginal Candidiasis-Associated Strains

A New Phenotype in Candida-Epithelial Cell Interaction Distinguishes Colonization- versus Vulvovaginal Candidiasis-Associated Strains

ABSTRACT Vulvovaginal candidiasis (VVC) affects nearly 3/4 of women during their lifetime, and its symptoms seriously reduce quality of life. Although Candida albicans is a common commensal, it is unknown if VVC results from a switch from a commensal to pathogenic state, if only some strains can cau...

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Bibliographic Details
Main Authors: Arianna Sala, Andrea Ardizzoni, Luca Spaggiari, Nikhil Vaidya, Jane van der Schaaf, Cosmeri Rizzato, Claudio Cermelli, Selene Mogavero, Thomas Krüger, Maximilian Himmel, Olaf Kniemeyer, Axel A. Brakhage, Benjamin L. King, Antonella Lupetti, Manola Comar, Francesco de Seta, Arianna Tavanti, Elisabetta Blasi, Robert T. Wheeler, Eva Pericolini
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mBio
Subjects:
Candida albicans
epithelial cells
host-pathogen interactions
interferons
vulvovaginal candidiasis
Online Access:https://journals.asm.org/doi/10.1128/mbio.00107-23

Internet

https://journals.asm.org/doi/10.1128/mbio.00107-23

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